Molecular BiologyFASEB BioAdvancesPeer-reviewed
Osteocalcin binds to the GPRC6A Venus fly trap allosteric site to positively modulate GPRC6A signaling
Rupesh Agarwal, Rui-Song Ye, Micholas Dean Smith…·Min Pi
This study shows that osteocalcin binds to a distinct allosteric site in GPRC6A's VFT domain, acting as a positive modulator and enhancing its signaling.
3 citations