Laurie Peverini

This study uses protein semi-synthesis and voltage-clamp fluorometry to track real-time conformational changes in the cardiac sodium channel NaV1.5 during inactivation.

The paper introduces an optonanobody that reversibly photoactivates native alpha7 nicotinic receptors without genetic modification, demonstrating its effectiveness in Xenopus oocytes and hippocampal slices.

This study investigates two Kir2.1 mutants linked to Andersen-Tawil syndrome, showing they impair channel function through distinct mechanisms, with C154Y causing dominant-negative effects.

This study uses voltage-clamp fluorometry to map conformational changes in the 5-HT3 serotonin-gated channel, linking them to electrophysiological states and agonist effects.