Molecular BiologyAnnals of Translational MedicinePeer-reviewed
In vitro assessment of an engineered tBID-based safety switch system in human T lymphocytes
Jiamiao Lu, Patrick J. Collins, Ki Jeong Lee…·Songli Wang
This study develops and tests a tBID-based safety switch system for engineered T cells to manage toxicity and persistence, showing up to 90% cell elimination in vitro.
DOI 10.21037/atm-21-443