Molecular BiologybioRxivPreprint
Proteoform-level deconvolution reveals a broader spectrum of ibrutinib off-targets
Isabelle Rose Leo, Elena Kunold, Anastasia Audrey…·Rozbeh Jafari
This study identifies additional proteoform targets of ibrutinib using thermal proteome profiling, revealing off-target interactions linked to immunomodulation and cellular processes.
DOI 10.1101/2023.11.14.566837