Author

Amir Esrafilian

University of Eastern FinlandORCID 0000-0002-8321-8528Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Approach:deep learning· 2 Assay:imaging· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Rami Kristian KorhoneniD· 3 shared Alan Jay GrodzinskyiD· 1 shared Anne‐Mari MustoneniD· 1 shared Anthony A. GattiiD· 1 shared Atte S. A. EskelineniD· 1 shared Cristina FloreaiD· 1 shared David G. LloydiD· 1 shared David J. SaxbyiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBioengineering

Rami Kristian KorhonenORCID

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3 papers

Recent·Most cited

BioengineeringPLoS Computational BiologyPeer-reviewedOct 31, 2025

Time-dependent computational model of post-traumatic osteoarthritis to estimate how mechanoinflammatory mechanisms impact cartilage aggrecan content

Atte S. A. Eskelinen, Joonas P. Kosonen, Moustafa Hamada…·Rami Kristian Korhonen

The paper develops a computational model to estimate how mechanoinflammatory mechanisms affect cartilage aggrecan content over time following joint injury.

5 citations

mechanistic / dynamical modelchromatin & epigenetic regulation

𝕏 PostBluesky

BioengineeringIEEE Transactions on Biomedical EngineeringPeer-reviewedSep 5, 2024

An Automated and Robust Tool for Musculoskeletal and Finite Element Modeling of the Knee Joint

Amir Esrafilian, Shekhar S. Chandra, Anthony A. Gatti…·Rami Kristian Korhonen

The paper develops an automated knee musculoskeletal finite element modeling pipeline and compares two approaches for generating biomechanical models.

31 citationstop 1%

humanimaging

𝕏 PostBluesky

BioengineeringbioRxivPreprintJun 27, 2024

Joint and tissue mechanics in post-traumatic osteoarthritis: insights from the rat model

Judith Piet, Amir Esrafilian, Seyed Ali Elahi…·Ilse Jonkers

This study uses a rat model to assess joint and tissue mechanics in post-traumatic osteoarthritis, finding no increased mechanical loading in the medial compartment despite structural changes.

DOI 10.1101/2024.06.27.601039

ratimaging

𝕏 PostBluesky