Author

Karim Aljakouch

German Cancer Research CenterORCID 0000-0002-8330-512XUnclaimed ORCID profile · follow to get notified of new preprints

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Organism:human· 4 Assay:proteomics· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Assay:ChIP-seq· 2 Approach:deep learning· 2

Frequent Co-Authors

Jeroen KrijgsveldiD· 4 shared Thomas G. P. GrünewaldiD· 4 shared Florian H. GeyeriD· 3 shared Alina Ritter· 2 shared Clémence HenoniD· 2 shared Florencia Cidre‐AranaziD· 2 shared Jing LiiD· 2 shared Olivier DelattreiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersCancer Biology

Jeroen KrijgsveldORCID

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4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 17, 2026

Oncogenic fusions induce an extensive cancer-restricted cryptic proteome in Ewing sarcoma

Luuk A. Broeils, Jill Pilet, Maria K. Koshkina…·Sebastiaan van Heesch

The paper shows EWSR1::FLI1 fusion drives the production of cancer-specific neoproteins in Ewing sarcoma, revealing a reversible dark proteome with therapeutic potential.

DOI 10.64898/2026.09.16.751792

humanscRNA-seq

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Cancer BiologybioRxivPreprintAug 5, 2025

Exploration of oncogenic cooperation between germline variation and somatic mutation in prostate cancer progression

Zuzanna Kolodynska, Kimberley M. Hanssen, Florian H. Geyer…·Thomas G. P. Grünewald

This study identifies PTPRK as a gene modulated by TMPRSS2::ERG fusion and a regulatory SNP, showing its role in prostate cancer progression and potential as a biomarker.

DOI 10.1101/2025.08.05.668679

humanbulk RNA-seq

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Cancer Biology癌症：英文版Peer-reviewedMar 15, 2025

Super-enhancer-driven CACNA2D2 is an EWSR1::WT1 signature gene encoding a diagnostic marker for desmoplastic small round cell tumor (DSRCT)

Florian H. Geyer, Alina Ritter, Seneca S. Kinn-Gurzo…·Florencia Cidre‐Aranaz

The paper identifies CACNA2D2 as a super-enhancer-driven target of EWSR1::WT1 and demonstrates its utility as a diagnostic biomarker for DSRCT.

12 citationstop 4%

humanscRNA-seq

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Cancer BiologyClinical ProteomicsPeer-reviewedJul 5, 2024

A single-sample workflow for joint metabolomic and proteomic analysis of clinical specimens

Hagen M. Gegner, Thomas Naake, Karim Aljakouch…·Jeroen Krijgsveld

The paper introduces a single-sample workflow, MTBE-SP3, for simultaneous proteomic and metabolomic analysis, showing it reduces technical variation and enables consistent results across biological matrices.

18 citations

humanproteomics

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