Author

Charlotte A. Dodson

Imperial College LondonORCID 0000-0002-8403-726XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Assay:imaging· 1

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Liming YingiD· 1 shared Paul GirvaniD· 1 shared

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1 shared paperBiophysics

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BiophysicsChemical CommunicationsPeer-reviewedJan 1, 2025

Tetramethylrhodamine self-quenching is a probe of conformational change on the scale of 15 - 25 Angstroms

Paul Girvan, Liming Ying, Charlotte A. Dodson

The paper determines the distance-dependence of TMR self-quenching and bounds its dissociation timescale, validating it as an alternative to FRET for conformational change detection.

DOI 10.1039/d4cc04524f

imagingexperimental assay

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