Jordan Little

The paper uses evolutionary rate covariation across malaria parasite species to infer protein interactions and identify new functional candidates.

ERC2.0 improves functional interaction prediction across large phylogenies by enhancing algorithm speed, normalization, and statistical power.

The paper evaluates the reliability of phylogenetic inference using primate enamel proteins by simulating sequence fragmentation and comparing results to a reference species tree.

The paper identifies potential genetic modifiers of Congenital Disorders of Glycosylation (CDG) using evolutionary rate covariation analysis across glycosylation pathways and other biological processes.

This study investigates whether evolutionary rate covariation (ERC) signals reflect physical interactions or other factors, finding weak evidence for physical coevolution and suggesting selective pressures may drive the signal.

The paper shows gadusol, a maternal compound in zebrafish, protects embryos from UV damage by reducing DNA damage markers, and its biosynthesis pathway is conserved in teleosts but lost in species without UV exposure.