Author

Prachi N. Ghule

University of VermontORCID 0000-0002-8640-5070Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

Gary S. SteiniD· 3 shared Janet Lee SteiniD· 2 shared Seth E. FrietzeiD· 2 shared Abigail G. Person· 1 shared Adam Officer· 1 shared Alexa GlenceriD· 1 shared Alexander D. BorowskyiD· 1 shared Alquassem Abuorquob· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCancer Biology

Gary S. SteinORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 28, 2026

Acute degron-mediated RUNX1 loss reprograms enhancer activity to epigenetically drive epithelial destabilization and initiate cancer hallmarks

Andrew J. Fritz, Haley W. Greenyer, Louis Dillac…·Gary S. Stein

This study shows that acute RUNX1 loss reprograms enhancer activity, leading to epithelial destabilization and cancer hallmark activation in human mammary epithelial cells.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintDec 29, 2025

IKAROS Gene Regulatory Network Reveal ERG as a Vulnerability in B-cell Acute Lymphoblastic Leukemia

Hana Paculová, Alyssa R. Richman, Joseph Boyd…·Seth E. Frietze

This study identifies ERG as a vulnerability in IKZF1-mutated B-cell acute lymphoblastic leukemia through gene regulatory network analysis and functional validation.

DOI 10.64898/2025.12.29.696402

humanscRNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintDec 1, 2023

Tumor microenvironmental determinants of high-risk DCIS progression

Alexa Glencer, Kirithiga Ramalingam, Nicole J. Schindler…·Alexander D. Borowsky

This study identifies immune microenvironment features and myoepithelial continuity as key determinants of progression in high-risk DCIS.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky