Motoki Takaku

This study shows that inhibiting the p38-MK2 pathway enhances the effectiveness of microtubule inhibitors in breast cancer cells while sparing normal cells.

The paper uses spatial ATAC-seq to identify chromatin accessibility changes in glial cells of Alzheimer's disease mouse models, linking them to AD-related pathways and human risk genes.

This study introduces 4x and 12x 3D-ExM methods for super-resolution microscopy, achieving nanometer-scale resolution for visualizing cellular structures.

This study shows CHD4 prevents inappropriate gene activation by editing transcription factor binding site selection through chromatin remodeling in breast cancer cells and during reprogramming.

This study investigates how a GATA3 mutation affects the transcriptional network involving ER, FOXA1, and GATA3, showing disrupted cooperation and altered chromatin localization.