Author

Elizabeth Wei-Chia Luo

California Institute of TechnologyORCID 0000-0002-8663-0446Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:machine learning (classical)· 1 Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1 Assay:structural biology· 1 Organism:virus· 1 Organism:yeast· 1

Frequent Co-Authors

Gerard C. L. WongiD· 3 shared Haleh AlimohamadiiD· 3 shared Kelsey A NoldeniD· 2 shared Liting DuaniD· 2 shared R. Blake HilliD· 2 shared Rena YangiD· 2 shared Shivam GuptaiD· 2 shared Taraknath MandaliD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersBiophysics

Gerard C. L. WongORCID

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3 papers

Recent·Most cited

BiophysicsJournal of the American Chemical SocietyPeer-reviewedJul 8, 2025

Drp1 Proteins Released from Hydrolysis-driven Scaffold Disassembly Trigger Nucleotide-dependent Membrane Remodeling to Promote Scission

Elizabeth Wei-Chia Luo, Kelsey A Nolden, Haleh Alimohamadi…·Gerard C. L. Wong

The paper investigates the mechanism of mitochondrial fission by Drp1, showing that GTP hydrolysis enables free Drp1 to induce membrane negative Gaussian curvature, promoting scission.

4 citations

machine learning (classical)cell signaling & trafficking

𝕏 PostBluesky

BiophysicsJournal of the American Chemical SocietyPeer-reviewedJul 8, 2025

Dynamins combine mechano-constriction and membrane remodeling to enable two-step mitochondrial fission via a snap-through instability.

Haleh Alimohamadi, Elizabeth Wei-Chia Luo, Xiaoying Liu…·Gerard C. L. Wong

This study shows how dynamin proteins use mechano-constriction and membrane curvature to drive mitochondrial fission through a snap-through instability.

4 citations

mechanistic / dynamical modelcell signaling & trafficking

𝕏 PostBluesky

BiophysicsACS NanoPeer-reviewedJun 5, 2024

Comparing multifunctional viral and eukaryotic proteins for generating scission necks in membranes

Haleh Alimohamadi, Elizabeth Wei-Chia Luo, Shivam Gupta…·Gerard C. L. Wong

This study compares the membrane scission capabilities of viral and eukaryotic proteins using mechanical models and SAXS data to analyze how lipid composition and interfacial tension affect neck size.

7 citations

virusyeast

𝕏 PostBluesky