NeuroscienceeLifePeer-reviewed
The role of matrix metalloproteinase-9 (MMP-9) in neurodevelopmental deficits and experience-dependent structural plasticity in Xenopus laevis tadpoles
Sayali V. Gore, Eric J. James, Lin-Chien Huang…·Carlos D. Aizenman
This study shows that elevated MMP-9 activity during early neurodevelopment causes neural circuit hyperconnectivity and behavioral deficits in Xenopus tadpoles, which can be reversed by blocking MMP-9.
24 citations