Author

Lin-Chien Huang

Scripps Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Hollis T. ClineiD· 2 shared Aaron C. Ta· 1 shared Adrian C. ThompsoniD· 1 shared Andrea P. BerghellaiD· 1 shared Carlos D. AizenmaniD· 1 shared Caroline R. McKeowniD· 1 shared Eric J. James· 1 shared Hai‐yan HeiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Hollis T. ClineORCID

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2 papers

Recent·Most cited

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedJan 10, 2024

BRCA1 and ELK-1 regulate Neural Progenitor Cell Fate in the Optic Tectum in response toVisual Experience in Xenopus laevis tadpoles

Lin-Chien Huang, Caroline R. McKeown, Hai‐yan He…·Hollis T. Cline

The paper identifies BRCA1 and ELK-1 as regulators of visual experience-dependent neural progenitor cell fate in Xenopus laevis optic tectum using transcriptomic and in vivo imaging analyses.

9 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky

NeuroscienceeLifePeer-reviewedJul 20, 2021

The role of matrix metalloproteinase-9 (MMP-9) in neurodevelopmental deficits and experience-dependent structural plasticity in Xenopus laevis tadpoles

Sayali V. Gore, Eric J. James, Lin-Chien Huang…·Carlos D. Aizenman

This study shows that elevated MMP-9 activity during early neurodevelopment causes neural circuit hyperconnectivity and behavioral deficits in Xenopus tadpoles, which can be reversed by blocking MMP-9.

24 citations

experimental assay

𝕏 PostBluesky