Author

Wai Soon Chan

National Institutes for Quantum Science and TechnologyORCID 0000-0002-8666-8778Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Approach:graph neural network· 1 Assay:Hi-C· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Chi-Hong Chang Chien· 1 shared Christopher Llynard D. OrtiziD· 1 shared Hidetoshi KonoiD· 1 shared Jinhao ZouiD· 1 shared Lee‐Wei YangiD· 1 shared Rong‐Long Pan· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 10 mutual co-author links

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1 shared paperBioinformatics

Chi-Hong Chang Chien

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintSep 22, 2025

HiC-SCA: A Spectral Clustering Method for Reliable A/B Compartment Assignment From Hi-C Data

Wai Soon Chan, Hidetoshi Kono

HiC-SCA improves A/B compartment assignment from Hi-C data through spectral clustering with noise filtering and resolution selection, showing better consistency across datasets.

1 citation

Hi-Cstatistical model

𝕏 PostBluesky

BioinformaticsBioinformaticsPeer-reviewedJul 24, 2019

DR-SIP: Protocols for Higher Order Structure Modeling with Distance Restraints- and Cyclic Symmetry-Imposed Packing

Wai Soon Chan, Jinhao Zou, Christopher Llynard D. Ortiz…·Lee‐Wei Yang

The paper introduces two filters, DR and SIP, to improve quaternary structure prediction for transmembrane proteins using distance restraints and cyclic symmetry.

2 citations

protein structurestatistical model

𝕏 PostBluesky