Examining Sleep Signals at the Cradle of Life: Can phylogenomic analysis of the Last Universal Common Ancestor (LUCA) reveal the fundamental role of sleep?
Seithikurippu Ratnas Pandi-Perumal, Konda Mani Saravanan, D. Warren Spence…·Saravana Babu Chidambaram
This paper uses phylogenomic analysis to examine sleep-related genes in LUCA, finding conserved genes linked to signaling, metabolism, and circadian rhythms, suggesting their fundamental role in evolution.