Author

Wenbin Zhang

National Institute of Biological Sciences, BeijingORCID 0000-0002-8746-0792Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Fan XuiD· 1 shared Hongbin LiuiD· 1 shared Jia GuoiD· 1 shared Jianhua SuiiD· 1 shared Jie CheniD· 1 shared Jie FuiD· 1 shared Jing WangiD· 1 shared Jiuchang ZhongiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioinformatics

Fan XuORCID

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2 papers

Recent·Most cited

PathologyProceedings of the National Academy of SciencesPeer-reviewedAug 23, 2024

LRG1 promotes atherosclerosis by activating macrophages

Juan Wang, Jing Wang, Jiuchang Zhong…·Xiaodong Wang

This study identifies LRG1 as a pro-inflammatory factor in atherosclerosis by promoting macrophage M1 polarization through ERK and JNK pathways, and shows that LRG1 inhibition reduces atherosclerosis progression.

42 citationstop 2%

mousebulk RNA-seq

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMar 9, 2024

Interpretable antibody-antigen interaction prediction by introducing route and priors guidance

Yutian Liu, Zhiwei Nie, Jie Chen…·Yonghong Tian

This paper introduces S3AI, an interpretable method for predicting antibody-antigen interactions by combining structural knowledge and chemical rules, outperforming existing models and identifying key CDR regions.

5 citations

protein sequencestatistical model

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