Author

Santosh Manicka

Tufts UniversityORCID 0000-0002-8747-2363Unclaimed ORCID profile · follow to get notified of new preprints

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Santosh Manicka1 paper · Allen Discovery Center at Tufts University;

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Developmental Biology· 1 Systems Biology· 1

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Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Michael G. LeviniD· 2 shared David MurrugarraiD· 1 shared Kathleen JohnsoniD· 1 shared Vaibhav P. PaiiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

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4 top collaborators · 4 mutual co-author links

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2 shared papersDevelopmental Biology

Michael G. LevinORCID

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2 papers

Recent·Most cited

Developmental BiologyiSciencePeer-reviewedNov 4, 2023

Information integration during bioelectric regulation of morphogenesis in the embryonic frog brain

Santosh Manicka, Vaibhav P. Pai, Michael G. Levin

The paper develops a bioelectric-genetic dynamical model to understand how spatial voltage patterns influence gene expression and brain development in Xenopus embryos, revealing mechanisms of information integration and plasticity.

15 citations

machine learning (classical)

𝕏 PostBluesky

Systems Biologynpj Systems Biology and ApplicationsPeer-reviewedApr 4, 2023

The nonlinearity of regulation in biological networks

Santosh Manicka, Kathleen Johnson, Michael G. Levin, David Murrugarra

The paper analyzes regulatory nonlinearity in biological networks using Boolean models and finds that biological regulation is generally less nonlinear than expected, with cancer networks showing higher and more variable nonlinearity.

38 citations

statistical model

𝕏 PostBluesky