Author
The University of Texas at San Antonio Health Science CenterORCID 0000-0002-8791-5849Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Hector Gonzalez‐Cantu, Viviane Nascimento Da Conceicao, S. Yusra Munawar…·Patricia L. M. Dahia
This study identifies TMEM127 as a critical regulator of the MHC-I degradation complex by modulating WWP2 activity, offering a target for enhancing antigen presentation in cancer immunology.
Zhijun Qiu, Jihane Khalife, Purushoth Ethiraj…·Ricardo C.T. Aguiar
This study shows that IRF8 mutations in DLBCL lymphomas impair antigen processing and presentation by reducing CD74 and HLA-DM, leading to immune evasion and increased tumor burden.
Shahida K. Flores, Yilun Deng, Ming Soon Cheng…·Patricia L. M. Dahia
The paper functionally characterizes germline TMEM127 variants, identifying pathogenic mutations and revealing a fourth transmembrane domain and an endocytic motif.