Author

Daan Dierickx

KU LeuvenORCID 0000-0002-8917-022XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

Jan CoolsiD· 2 shared Marlies Vanden BemptiD· 2 shared Alexandra Bacquelaine VelosoiD· 1 shared Anaís Sánchez‐CastilloiD· 1 shared Annalisa OcchipintiiD· 1 shared Claudio AngioneiD· 1 shared Elien HeyleniD· 1 shared Félicien Renard· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Jan CoolsORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 19, 2026

Sertraline and Carfilzomib Synergize to Target T-cell Malignancies with Serine/Glycine synthesis activity via Cholesterol Dysregulation, Cellular Stress and Immune Modulation

Paulien Verstraete, Elien Heylen, Anaís Sánchez‐Castillo…·Kim De Keersmaecker

This paper shows that sertraline and carfilzomib work together to kill T-cell cancers by disrupting metabolism and changing the immune environment.

DOI 10.64898/2026.08.17.744660

mouseproteomics

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Cancer BiologybioRxivPreprintMar 3, 2024

Dual targeting of EZH2 and Histone Deacetylases in hematological malignancies promotes transcriptional and metabolic deregulation leading to ferroptosis

Alexandra Bacquelaine Veloso, Thomas Slegers, Jente M. Schoenaker…·Marlies Vanden Bempt

This study shows that targeting EZH2 and HDACs together induces ferroptosis in hematological malignancies by upregulating cholesterol biosynthesis and causing metabolic stress.

DOI 10.1101/2024.03.03.583195

humanbulk RNA-seq

𝕏 PostBluesky