Author
Yixuan Wang
Chinese University of Hong KongORCID 0000-0002-8989-3129Unclaimed ORCID profile · follow to get notified of new preprints
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Biology Disciplines
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2021-2026 · peak 4/yrCo-Author Collaboration Network
10 top collaborators · 32 mutual co-author links9 papers
Recent·Most cited
- BioinformaticsLecture notes in computer sciencePeer-reviewed
cfDecon: Accurate and Interpretable methylation-based cell type deconvolution for cell-free DNA
Yixuan Wang, Jiayi Li, Jingqi Li…·Yu Li
cfDecon improves cfDNA deconvolution accuracy and interpretability using deep learning, outperforming existing methods in simulation and clinical datasets.
2 citationstop 4% - BioinformaticsBioinformaticsPeer-reviewed
AcrNET: Predicting Anti-CRISPR with Deep Learning
Yunxiang Li, Yumeng Wei, Sheng Yong Xu…·Yu Li
AcrNET predicts anti-CRISPR proteins using a deep learning model, achieving significant performance improvements and class-level predictions.
27 citations - BioinformaticsNature CommunicationsPeer-reviewed
Deep autoencoder for interpretable tissue-adaptive deconvolution and cell-type-specific gene analysis
Yanshuo Chen, Yixuan Wang, Yuelong Chen…·Yu Li
TAPE deconvolves bulk RNA-seq data into cell-type fractions and gene expression using a deep autoencoder, showing better performance and robustness compared to existing methods.
93 citationstop 2% - BioinformaticsbioRxivPreprint✦ In-depth digest
Interpretable RNA Foundation Model from Unannotated Data for Highly Accurate RNA Structure and Function Predictions
Jiayang Chen, Zhihang Hu, Siqi Sun…·Yu Li
A BERT-style model pretrained on 23.7 million unlabelled ncRNA sequences gives embeddings that improve secondary structure, contact, distance-map and some function predictions over task-specific and MSA-based baselines.
247 citations - BioinformaticsbioRxivPreprint
scMinerva: an Unsupervised Graph Learning Framework with Label-efficient Fine-tuning for Single-cell Multi-omics Integrated Analysis
Tingyang Yu, Yongshuo Zong, Yixuan Wang…·Yu Li
scMinerva is an unsupervised graph learning framework for single-cell multi-omics analysis that outperforms existing methods with few labels and provides biomarkers for COVID-19 cell differentiation.
- BioinformaticsbioRxivPreprint✦ In-depth digest
conST: an interpretable multi-modal contrastive learning framework for spatial transcriptomics
Yongshuo Zong, Tingyang Yu, Xuesong Wang…·Yu Li
conST learns embeddings from gene expression, spatial neighbors, and histology via three-level contrastive learning, reaching adjusted Rand index 0.65 on spatialLIBD slice 151673, with GNNExplainer-based explanations.
- BioinformaticsbioRxivPreprint
Contrastive Cycle Adversarial Autoencoders for Single-cell Multi-omics Alignment and Integration
Xuesong Wang, Zhihang Hu, Tingyang Yu…·Yu Li
This paper introduces a framework to align and integrate single-cell RNA-seq and ATAC-seq data, achieving higher accuracy than existing methods on both simulated and real data.
3 citations - BioinformaticsbioRxivPreprint
CLMB: deep contrastive learning for robust metagenomic binning
Pengfei Zhang, Zhengyuan Jiang, Yixuan Wang, Yu Li
CLMB improves metagenomic binning by using deep contrastive learning to handle noise, outperforming existing methods and recovering more high-quality genomes.
4 citations