Sarah J. Wheelan

The paper identifies genomically stable regions in metastatic pancreatic cancer that can be targeted by CRISPR-Cas9 due to preserved PAM sites, suggesting a potential gene therapy approach.

The paper describes AnVIL, a cloud-based platform that enables genomic data analysis without data transfer, improving security, scalability, and collaboration.

Hobotnica estimates molecular signature quality by assessing their ability to stratify data and assign significance scores for comparing different groups.

StereoGene estimates genomewide correlation of continuous genomic features, revealing spatial relationships between epigenomic features and splicing sites.