Author

James L. Cole

University of ConnecticutORCID 0000-0002-9028-8364Unclaimed ORCID profile · follow to get notified of new preprints

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Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1

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Aaron G. Feinstein· 1 shared Eric R. MayiD· 1 shared

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2024-2024 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperBiophysics

Aaron G. Feinstein

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1 paper

Recent·Most cited

BiophysicsThe Journal of Physical Chemistry BPeer-reviewedSep 18, 2024

The αC helix is a central regulator of PKR activation

Aaron G. Feinstein, James L. Cole, Eric R. May

This study investigates the structural mechanism of PKR activation, showing that back-to-back dimerization stabilizes a catalytically competent conformation through the C helix.

1 citation

biophysical modelingchromatin & epigenetic regulation

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