Ruth McPherson

The paper examines the functional differences of ZFAS1 isoforms by targeting specific exons and identifies shared and antagonistic effects on cell cycle and translation.

The paper validates HepaRG cells as a model for studying TRIBAL, showing functional overlap with hepatocytes and highlighting TRIBAL's role in metabolic regulation.

This study shows COP1 maintains HNF4A function in primary hepatocytes and HepG2 cells but not HuH-7 cells, challenging previous links between COP1 and hepatic tumorigenesis.

This study investigates the impact of heterozygous ABCG5 LoF variants on LDL-C levels and CAD risk, finding a significant association with elevated LDL-C and doubled CAD risk.

The paper identifies a missense variant in the MARC1 gene associated with protection against cirrhosis and lower liver enzyme and cholesterol levels.