Connie Jiang

This study shows that NRF2 activation by erythrophagocytosis suppresses the IL-12-IFNg-IL-10 axis, reducing hyperinflammation in a murine model of hyperinflammatory disease.

The paper identifies molecular factors that mark pluripotency potential in rare somatic cells by analyzing fibroblast reprogramming efficiency.

The paper establishes a functional patch clamp assay to classify KCNH2 variants in LQTS, using Z-scores to inform ACMG criteria and correlate with clinical scores.

ClonoCluster combines clonal origin and transcriptome data to create hybrid clusters, revealing biologically relevant markers across six datasets.

This study uses a high-throughput patch-clamp assay to reclassify KCNH2 variants of uncertain significance, providing evidence for clinical interpretation.

The paper investigates cell type determination during cardiac differentiation of hiPS cells, finding that cell type specification begins shortly after seeding and is cell-autonomous.

The paper identifies that parvocellular oxytocin neurons are critical for autism-related social reward behavior and show enrichment of autism risk genes in these neurons.

The paper identifies rare cell states in melanoma that contribute to drug resistance by analyzing single-cell gene expression and signaling dynamics.