Systems BiologybioRxivPreprint
Perturbational fitness analysis of CRISPR screens uncovers information-theoretic relation between gene function and selection
Aram Nikolai Andersen, Nathalia Chica, Laure Piechaczyk…·Jorrit M. Enserink
This study uses information theory to analyze CRISPR screens and quantifies gene function through geometric measures of selection dynamics and environmental perturbations.
DOI 10.1101/2025.04.29.651199