Alexander DeLuna

The paper identifies widespread Saccharomyces hybridization in agave fermentations, showing multiple independent origins and asymmetric parental genetic diversity.

The paper examines chronological lifespan (CLS) in Candida species, finding that longer CLS correlates with virulence in C. albicans but not across species.

The paper analyzes 178 genomes of Kluyveromyces marxianus to show two distinct evolutionary trajectories within the species, one linked to domestication and the other to deep lineage divergence.

The paper analyzes S. cerevisiae isolates from agave fermentation in Mexico, revealing geographical population structure and multiple introgression events in the Neotropics.

This study identifies retrotransposon dynamics and chromatin regulation as key mechanisms by which metformin extends lifespan in yeast.

This study identifies tRNA-mediated proteostasis as a mechanism by which SWR1C loss extends longevity in yeast.

The paper sequenced Hanseniaspora yeasts from agave fermentations, revealing dynamic gene loss across species and functional categories without clear phenotypic consequences.

This study examines the distribution and ecological divergence of Saccharomyces species in Mexican environments, revealing distinct population structures and dispersal patterns between wild and fermentative habitats.

The paper investigates how the branched-chain amino acid (BCAA) pathway is regulated during the diauxic shift in yeast and its impact on carbon metabolism.

This study identifies core genetic drivers of chronological aging in yeast through meta-analysis and functional screens, revealing Tec1 and mitochondrial machinery as key regulators.

This study analyzes microbial communities in agave fermentations across Mexico, finding that distillery-specific practices shape microbial composition, with core taxa present in most fermentations.

The paper introduces a quantitative method to identify subtelomeric silencing factors in budding yeast through genome-wide screening using a dual reporter system.

The paper introduces an optimized competitive-aging method to identify gene-drug interactions affecting yeast chronological lifespan, revealing a link between protein glycosylation and metformin-induced lifespan extension.

The paper maps binary interactions between transcription factors involved in gynoecium development in Arabidopsis, identifying over 200 protein-protein interactions and revealing dynamic sub-networks related to developmental subprocesses.

The paper identifies 472 yeast gene mutants affected by dietary restriction and highlights Ste12's role in lifespan extension through cell-cycle arrest.

The paper identifies non-catalytic phenotypes in yeast enzymes, suggesting moonlighting activities beyond their annotated functions.