Molecular BiologyJCI InsightPeer-reviewed
12-Lipoxygenase inhibition delays onset of autoimmune diabetes in human gene replacement mice
Titli Nargis, Charanya Muralidharan, Jacob R. Enriquez…·Raghavendra G. Mirmira
This study shows that inhibiting 12-LOX with VLX-1005 delays autoimmune diabetes onset in human gene replacement mice by altering inflammatory pathways and immune cell infiltration.
12 citations