Nadim Majdalani

Akkermansia expansion reduces short-chain fatty acid-producing Firmicutes in human-flora uveitis mice, raising Th1 responses and disease; a Verrucomicrobia/Firmicutes ratio is elevated in uveitis, MS and Crohn's patients.

This study determines the structures of Rcs phosphorelay components and describes how RcsF activates the system by modifying IgaA/RcsD interactions.

This paper identifies an sRNA, S17S, that downregulates multiple genes, including a sigma54 transcriptional activator, in the virulence mode of B. pertussis through complementary base pairing with ribosome binding sites.

This study identifies RcsF-independent mechanisms of Rcs phosphorelay activation in enterobacteria, revealing distinct roles for DsbA, DjlA, and DrpB in signal transduction.

The paper shows that a negative feedback loop involving RpoS and rssB is critical for restoring RpoS degradation after stress in E. coli.