Pei Xuan Er

This paper benchmarks spatial transcriptomics in stem cell-derived organoids using Stereo-seq, optimizing RNA capture and introducing regional analysis methods.

This study shows that hPSC-derived distal nephron epithelium can adopt ureteric or nephric duct-like identities in vitro in response to extracellular signals.

This study shows that distinct FGF subfamily members modulate nephron patterning in kidney organoids, with FGF8b and FGF10 having unique effects on proximal and distal nephron development.

The paper uses single-cell RNA-seq to analyze developing mouse kidney and human kidney organoids, identifying cell clusters and revealing insights into kidney development and organoid maturation.

The paper demonstrates the use of bioprinted kidney organoids for high content drug screening, showing reproducibility and response to doxorubicin toxicity.