BiophysicsProceedings of the National Academy of SciencesPeer-reviewed
Single-molecule dissection of CFTR folding defects and pharmacological rescue
Sang Ah Kim, Jesper Levring, Jue Chen, Tae‐Young Yoon
This study uses single-molecule magnetic tweezers to analyze CFTR folding defects and shows pharmacological correctors reshape the folding energy landscape by catalyzing transitions.
DOI 10.1073/pnas.2528216123