Author

Mohammed Alhusayan

University of PennsylvaniaORCID 0000-0002-9488-0752Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Arul M. ChinnaiyaniD· 2 shared Erick Mitchell-VelasqueziD· 2 shared Irfan Ahmed AsanganiiD· 2 shared Rahul MannaniD· 2 shared Sharan VenkateshiD· 2 shared Abhijit ParoliaiD· 1 shared Aqsa Yashfeen· 1 shared Benjamin Garcia· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Arul M. ChinnaiyanORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 1, 2026

NNMT Loss Drives Cancer Progression by enhancing SAM availability for mTORC1 Signaling and Chromatin Methylation

Qu Deng, Erick Mitchell-Velasquez, Sharan Venkatesh…·Irfan Ahmed Asangani

This study identifies NNMT as a tumor suppressor in prostate cancer that regulates SAM availability, mTORC1 signaling, and chromatin methylation, revealing a therapeutic strategy using dietary methionine restriction and mTORC1 inhibition.

DOI 10.64898/2026.06.30.734970

mousehuman

𝕏 PostBluesky

Cancer BiologyNature GeneticsPeer-reviewedSep 9, 2024

NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis

Abhijit Parolia, Sanjana Eyunni, Brijesh Kumar Verma…·Irfan Ahmed Asangani

This study identifies NSD2 as a critical component of the AR neo-enhanceosome in prostate cancer, showing its role in AR enhancer circuitry and tumor progression.

45 citationstop 2%

humanChIP-seq

𝕏 PostBluesky