Cancer BiologybioRxivPreprint
The Phospholipase A2 Activity of Peroxiredoxin 6 Protects Hepatocarcinoma Cells Against Ferroptosis and Mitophagy Impairment
Angel Ortiz-Alcantara, Alberto Ortiz-Olivencia, Raul Gonzalez-Ojeda…·Carmen Alicia Padilla
This study shows that PRDX6's iPLA2 activity protects hepatocarcinoma cells from ferroptosis by maintaining lipid homeostasis and mitophagy.
DOI 10.64898/2026.11.06.764823