Chao-Yin Cheng

This paper shows that VPS8D, a CORVET subunit in Tetrahymena thermophila, is essential for maintaining the contractile vacuole complex (CVC) structure and function, as its knockdown leads to disassembly of CVC components and increased osmotic sensitivity.

The paper identifies four proteins that localize to distinct zones of the contractile vacuole complex in Tetrahymena thermophila, enabling in vivo analysis of its dynamics and structure.