Srinivasaraghavan Kannan

The paper identifies pathogenic PD-L1 nsSNVs that alter glycosylation and ICI binding through bioinformatics and experimental methods.

This paper identifies evolutionarily conserved LRR proteins in velvet worm slime that form receptor-like structures, enabling reversible supramolecular network formation in bioadhesive fibers.

This study shows RA signaling promotes luminal identity in prostate progenitors through Foxa1, and identifies a loss-of-function mutation in Foxa1 linked to prostate cancer dedifferentiation.

The paper investigates how surface charge mutations affect PETase activity on different PET substrates and identifies an engineered variant with improved degradation efficiency.