Florian Rohart

This study estimates non-additive genetic variance in human complex traits using a large sample of unrelated individuals and finds that additive variance is predominant while dominance and epistatic variances are negligible.

DIABLO identifies multi-omics biomarker panels to distinguish phenotypic groups, showing better biological enrichment than other methods in simulated and real datasets.

The paper introduces mixOmics, an R package for multivariate analysis of omics data, focusing on integration and visualization of heterogeneous datasets.