BioengineeringNature CommunicationsPeer-reviewed
Single-cell multiplex approaches deeply map ON-target CRISPR-genotoxicity and reveal its mitigation by palbociclib and long-term engraftment
Julian Boutin, Sabrina Fayet, V Terribile Wiel Marin…·Aurélie Bedel
The paper develops a multiplexed single-cell approach to monitor CRISPR-induced genotoxicity and shows that palbociclib reduces genomic rearrangements in hematopoietic cells.