Author

Chenxu Guo

Harvard UniversityORCID 0000-0002-9651-4203Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew S PekosziD· 1 shared Bryce OrdwayiD· 1 shared Eric F. ZaniewskiiD· 1 shared Esther RheinbayiD· 1 shared Garrett Lam· 1 shared Gary X. WangiD· 1 shared Ilze SmidtiD· 1 shared Ioannis SanidasiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

Andrew S PekoszORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 9, 2026

A SIRT5-induced metabolic switch underlies chemoresistance and ATR checkpoint dependence in triple-negative breast cancer

Zuen Ren, Tiziano Bernasocchi, Kiran Kurmi…·Leif William Ellisen

This study identifies SIRT5-induced metabolic changes as a driver of chemoresistance in TNBC and reveals ATR checkpoint dependence as a therapeutic vulnerability.

DOI 10.64898/2026.04.07.716852

humanproteomics

𝕏 PostBluesky

BioengineeringbioRxivPreprintJan 4, 2024

Antigen-display exosomes provide adjuvant-free protection against SARS-CoV-2 disease at nanogram levels of spike protein

Chenxu Guo, Jaiprasath Sachithanandham, William Zhong…·Stephen J. Gould

This study demonstrates that antigen-display exosomes can induce strong neutralizing antibodies and protect against SARS-CoV-2 at nanogram levels of spike protein without adjuvant.

1 citation

experimental assayhost-pathogen & immune response

𝕏 PostBluesky