Author

Amal Kasri

Allen Institute for Brain ScienceORCID 0000-0002-9656-4710Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Gunnar BrinkmalmiD· 2 shared Henrik ZetterbergiD· 2 shared Marie‐Claude PotieriD· 2 shared Béatrice SchaackiD· 1 shared Catherine MarqueriD· 1 shared Diana PiotrowskaiD· 1 shared Elena CamporesiiD· 1 shared Eleni GkanatsiouiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Gunnar BrinkmalmORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 30, 2026

Differential endothelial cell remodeling in Down syndrome and APP duplication drives distinct blood brain barrier dysfunction

Louis Valay, Amal Kasri, Vincent Fontaine…·Marie‐Claude Potier

DOI 10.64898/2026.10.29.762815

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 16, 2020

Mutations in the juxtamembrane segment of the cholesterol-binding site of APP alter its processing and promotes production of shorter, less toxic Aβ peptides.

Linda Hanbouch, Béatrice Schaack, Amal Kasri…·Marie‐Claude Potier

This study shows that mutations in the juxtamembrane cholesterol-binding site of APP reduce production of toxic Aβ40 and Aβ42 peptides and increase shorter, less toxic Aβ peptides.

1 citation

humanproteomics

𝕏 PostBluesky