GenomicsNature BiotechnologyPeer-reviewed
Cell type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening
Jimin Tan, Nina Shenker-Tauris, Javier Rodriguez-Hernaez…·Aristotelis Tsirigos
This study introduces C.Origami, a deep learning model that predicts cell type-specific 3D chromatin organization, enabling in silico genetic screening to identify genomic regions affecting chromatin structure.