Systems BiologybioRxivPreprint
Time-Resolved Proteomics of a Polyglutamine-Expanded Huntingtin in vitro Cell Model Reveals Early RNA-Regulatory Compensation and Late Respiratory-Chain Remodeling
Ekin Sönmez, Pınar Mutlu, Cinla Ozlevent…·Hüseyin Çimen
This paper uses time-resolved proteomics to study mutant huntingtin's effects in vitro, revealing two distinct proteomic stages and identifying potential drug targets.
DOI 10.64898/2026.08.21.746221