Author

Thomas L. Maurissen

Kyoto UniversityORCID 0000-0002-9686-2400Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Knut WoltjeniD· 2 shared Tomoko MatsumotoiD· 2 shared A. Rizkallah· 1 shared Alex OdermattiD· 1 shared Alexander Y. LiuiD· 1 shared Angélique Augustin· 1 shared Ayako Nagahashi· 1 shared Barbara HöllbacheriD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBioengineering

Knut WoltjenORCID

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3 papers

Recent·Most cited

Cell BiologyStem Cell ReportsPeer-reviewedAug 21, 2025

ApoE4 disrupts intracellular trafficking and iron homeostasis in an improved iPSC-based model of human brain endothelial cells

Luisa Bell, Shane Clerkin, Filiz Sila Rizalar…·Roberto Villaseñor

The paper investigates how ApoE4 affects intracellular trafficking and iron homeostasis in human brain endothelial cells derived from iPSCs, showing altered endosomal organization and iron levels.

6 citations

humanbulk RNA-seq

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BioengineeringThe CRISPR JournalPeer-reviewedOct 1, 2024

Enrichment of allelic editing outcomes by Prime Editing in iPS cells

Ryo Niwa, Tomoko Matsumoto, Alexander Y. Liu…·Knut Woltjen

This study compares Cas9 and Prime Editing (PE) in human iPS cells, showing PE's superior precision and demonstrating how sorting by PE expression affects allelic editing outcomes.

5 citations

humanCRISPR screen

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Developmental BiologyNaturePeer-reviewedApr 1, 2020

Modeling the Human Segmentation Clock with Pluripotent Stem Cells

Mitsuhiro Matsuda, Yoshihiro Yamanaka, Maya Uemura…·Cantas Alev

This study models the human segmentation clock using iPSC-derived presomitic mesoderm, identifying oscillatory genes and validating disease-related gene effects.

206 citationstop 1%

humanbulk RNA-seq

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