BioinformaticsbioRxivPreprint
BoYueGRN: Zero-shot causal discovery of directed gene regulatory networks from single-cell transcriptomes via amortized inference over synthetic structural causal models
BoYueGRN infers directed gene regulatory networks from single-cell transcriptomes using synthetic structural causal models, achieving high directional accuracy on CRISPRi screens and disease-specific GRN dynamics.