Jingyi Fei

The paper uses super-resolution imaging and in situ sequencing to map RNA distribution within nucleolar subdomains, revealing distinct RNA populations and processing dynamics.

This study identifies sequence features that determine RNA localization to nuclear speckles, showing similarities with splicing codes and linking speckle localization to spliceosome assembly and splicing efficiency.

The paper shows that mRNAs condense broadly in yeast under stress, independent of length, and new transcripts escape this condensation for selective translation.

The paper investigates RNA localization to nuclear speckles and finds that splicing efficiency is linked to transcript enrichment in these organelles.

This study uses single-molecule FRET to analyze the binding mechanism of the Mycobacterium tuberculosis IleS T-box riboswitch, revealing a two-step model and the role of specific sequences in conformational flexibility and tRNA recognition.

This study investigates how single base-pair changes affect the in vivo kinetics of sRNA-target interactions, showing that Hfq facilitates annealing and buffers base-pair disruptions.

The paper uses single-molecule FRET to study how mismatches affect Cas9-RNA DNA binding and rejection kinetics, revealing that proximal mismatches lead to rapid rejection while distal mismatches allow stable complex formation.