Author

Kees R. Straatman

University of LeicesterORCID 0000-0002-9812-492XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:yeast· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Kayoko TanakaiD· 3 shared Ábel VértesyiD· 2 shared Andrew M. FryiD· 2 shared Chandni Parmar· 2 shared Cyril DomingueziD· 2 shared Edda KlippiD· 2 shared Emma J. Kelsall· 2 shared Gabriele Schreiber· 2 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCell Biology

Kayoko TanakaORCID

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4 papers

Recent·Most cited

Cell BiologyScientific ReportsPeer-reviewedJan 27, 2026

NEK7 phosphorylation of cortactin modulates the migratory capacity of cells expressing EML4-ALK V3

Emily L. Richardson, Axel Knebel, Kees R. Straatman…·Andrew M. Fry

This study identifies NEK7-mediated phosphorylation of cortactin as a mechanism by which EML4-ALK V3 enhances cell migration through actin cytoskeleton remodeling.

DOI 10.1038/s41598-026-36484-4

humanproteomics

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Cell BiologybioRxivPreprintMar 6, 2025

Constitutively active RAS prolongs Cdc42 signalling while attenuating MAPK signalling during fission yeast mating

Emma J. Kelsall, Akatsuki Kimura, Ábel Vértesy…·Kayoko Tanaka

This study shows that constitutively active RAS in fission yeast prolongs Cdc42 signaling while reducing MAPK signaling through competitive binding and feedback mechanisms.

2 citations

yeaststatistical model

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Cell BiologyJournal of Biological ChemistryPeer-reviewedMay 23, 2024

Endogenous oncogenic KRAS expression increases cell proliferation and motility in near-diploid hTERT RPE-1 cells

Naushin L. Hindul, Lauren R. Abbott, Sumaya M.D. Adan…·Kayoko Tanaka

This study shows that endogenous oncogenic KRAS mutations increase cell proliferation and motility in hTERT RPE-1 cells, with differential responses to targeted therapies.

6 citations

humanproteomics

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Molecular BiologybioRxivPreprintJan 29, 2019

Constitutively active RAS in S. pombe causes persistent Cdc42 signalling but only transient MAPK activation

Emma J. Kelsall, Ábel Vértesy, Kees R. Straatman…·Kayoko Tanaka

The paper shows that constitutively active Ras1.G17V in S. pombe causes prolonged Cdc42 activation but only transient MAPKSpk1 activation, with a model explaining the dynamics.

2 citations

yeaststatistical model

𝕏 PostBluesky