NeuroscienceNeuroImage ClinicalPeer-reviewed
Multi-compartment analysis of the complex gradient-echo signal quantifies myelin breakdown in premanifest Huntington's disease
Chiara Casella, Elena Kleban, Anne Rosser…·Derek Kenton Jones
This study uses multi-compartment MRI signal analysis to quantify myelin breakdown in premanifest Huntington's disease, finding reduced myelin water fraction and age-related executive function decline.