Author

Yasmeen N. Ruma

Howard Hughes Medical InstituteORCID 0000-0002-9817-8477Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:protein structure· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Tamir GoneniD· 3 shared Alex J. VecchioiD· 1 shared Alexandria M. Mandriota· 1 shared Angus C. GreyiD· 1 shared Anna ShiriaevaiD· 1 shared Anthony A. KossiakoffiD· 1 shared Charles R. SandersiD· 1 shared Chinemerem P. OgbuiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiophysics

Tamir GonenORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiophysicsPNAS NexusPeer-reviewedJun 1, 2025

Biophysical Basis of Paracellular Barrier Modulation by a Pan-Claudin-Binding Molecule

Chinemerem P. Ogbu, Mason de las Alas, Alexandria M. Mandriota…·Alex J. Vecchio

The paper develops a synthetic antibody fragment that binds to 10 claudin subtypes, opening tight junctions and modulating paracellular permeability.

6 citations

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

BiophysicsNature CommunicationsPeer-reviewedMar 26, 2025

Structure of the lens MP20 mediated adhesive junction

William J. Nicolas, Anna Shiriaeva, Michael W. Martynowycz…·Tamir Gonen

This study determines the structure of MP20, a lens membrane protein, revealing its tetrameric assembly and adhesive function in forming thin junctions essential for lens transparency.

17 citationstop 4%

humanprotein structure

𝕏 PostBluesky

BiochemistryJournal of Structural Biology XPeer-reviewedJul 6, 2024

MicroED structure of the C11 cysteine protease Clostripain

Yasmeen N. Ruma, Guanhong Bu, Johan Hattne, Tamir Gonen

This paper determines the structure of Clostripain using MicroED, revealing its catalytic dyad and substrate binding pocket.

DOI 10.1016/j.yjsbx.2024.100107

protein structureexperimental assay

𝕏 PostBluesky