Author

Arjun K. Aditham

Fred Hutch Cancer CenterORCID 0000-0002-9839-7733Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1 Organism:yeast· 1

Frequent Co-Authors

Caelan E. RadfordiD· 1 shared Caleb R. CarriD· 1 shared Jesse D. BloomiD· 1 shared Naveen JastiiD· 1 shared Neil P. KingiD· 1 shared Nicole V. DelRossoiD· 1 shared Peter SuzukiiD· 1 shared Polly Morrell FordyceiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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1 shared paperMicrobiology

Caelan E. RadfordORCID

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2 papers

Recent·Most cited

MicrobiologyCell Host & MicrobePeer-reviewedMay 20, 2025

Deep mutational scanning of rabies glycoprotein defines mutational constraint and antibody-escape mutations

Arjun K. Aditham, Caelan E. Radford, Caleb R. Carr…·Jesse D. Bloom

This study uses deep mutational scanning to identify functional and antigenic effects of mutations in rabies glycoprotein, revealing escape mutations for antibodies and constrained regions for vaccine development.

16 citationstop 2%

deep learningdrug response / drug discovery

𝕏 PostBluesky

BiophysicsbioRxivPreprintNov 13, 2023

High-throughput thermodynamic and kinetic measurements of transcription factor/DNA mutations reveal how conformational heterogeneity can shape motif selectivity

Renee Hastings, Arjun K. Aditham, Nicole V. DelRosso…·Polly Morrell Fordyce

The paper measures thermodynamic and kinetic properties of transcription factor/DNA mutations to show how conformational heterogeneity affects motif selectivity.

4 citations

humanyeast

𝕏 PostBluesky