Didier Flament

This study identifies Hib, a new family of ribosome hibernation factors in Archaea, showing its role in preserving ribosomes during stress and revealing its structural and functional mechanisms.

The paper identifies and classifies novel M42 peptidases in Archaea, revealing their functional diversity and evolutionary history through phylogenomic and structural analyses.

This study shows archaeal replication origins prevent replication-transcription conflicts and coordinate genetic information transfer, suggesting roles beyond DNA replication initiation.

The paper identifies aRNase J, a 5’-3’ exoribonuclease in Archaea, as part of a complex with ASH-Ski2 helicase and the RNA exosome, suggesting its role in RNA surveillance and translation.