Charlotta G. Lebedenko

This study demonstrates that O-glycosylation contributes to sialoglycoRNA biogenesis and shows increased sialylation in ulcerative colitis-derived organoids.

The paper identifies acp3U as the site where N-glycans attach to RNA in glycoRNA using rPAL and SWATH-MS.

The paper identifies heparan sulfate proteoglycans as key organizers of cell surface glycoRNA and RNA binding proteins, showing their role in regulating growth factor signaling.

This paper introduces rPAL, a method for detecting native sialoglycoRNAs with significantly improved sensitivity compared to existing methods, demonstrating its application in human clinical samples.