BioinformaticsBioinformaticsPeer-reviewed
End-to-end learning of multiple sequence alignments with differentiable Smith-Waterman
Samantha Petti, Nicholas Bhattacharya, Roshan Rao…·Sergey Ovchinnikov
This paper introduces a differentiable Smith-Waterman algorithm to jointly learn multiple sequence alignments and downstream tasks, showing improvements in contact prediction and structure prediction.
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